The Link Between Obstructive Sleep Apnoea and Neurodegeneration and Cognition

Abstract Purpose of Review Obstructive sleep apnoea (OSA) is increasingly found to have an impact on neurodegeneration. In this review, we summarise recent findings the association between OSA and brain morphology, cognition, processes related Alzheimer’s dementia (AD) Parkinson’s disease (PD). Recent Findings Associations alterations in grey white matter, diffusivity, deficits memory, attention, executive control were reported. Furthermore, was correlated with higher risks developing AD PD associated pathophysiology. Treatment alleviate but not reverse some damage. Summary There are strong indications that plays a major role neurodegenerative processes. The broad picture however remains elusive, likely due insufficient sample sizes, heterogeneous outcomes, definitions failing quantify disorder’s sub-processes. While studies resolving these issues required, available evidence shows be promising target slow neurodegeneration delay onset disorders.